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DeCS
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Descriptor English:
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Sequestosome-1 Protein
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Descriptor Spanish:
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proteína secuestosoma-1
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Descriptor Portuguese:
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Proteína Sequestossoma-1
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Synonyms English:
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EBI3 Associated Protein of 60 KDa
EBI3-Associated Protein of 60 KDa
EBIAP Protein
Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62 Kda
Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda
Sequestosome 1 Protein
Ubiquitin Binding Protein p62
Ubiquitin-Binding Protein p62
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Tree Number:
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D12.644.360.024.329
D12.776.094.750
D12.776.157.057.160
D12.776.476.024.422
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Definition English:
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A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56538
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Unique Identifier:
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D000071456
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Occurrence in VHL:
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Similar:
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DeCS
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